New drug combo takes on superbug pneumonia in hospitals

NCT ID NCT07512596

First seen Apr 08, 2026 · Last updated Apr 27, 2026 · Updated 2 times

Summary

This study tests whether a combination of intravenous and inhaled polymyxin E2 can safely treat pneumonia caused by carbapenem-resistant bacteria in hospitalized or ventilated patients. About 48 adults will receive either the experimental treatment or a control. The goal is to see if more patients achieve clinical cure and bacterial clearance.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Tsinghua Changgung Hospital

    Beijing, Beijing Municipality, 102200, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chengdu Third People's Hospital

    Chengdu, Sichuan, 610031, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • First Affiliated Hospital of Gannan Medical University

    Ganzhou, Jiangxi, 341000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Foshan Nanhai District People's Hospital

    Foshan, Guangdong, 528200, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Henan Provincial People's Hospital

    Zhengzhou, Henan, 450003, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Northern Jiangsu People's Hospital

    Yangzhou, Jiangsu, 225000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nuclear Industry 416 Hospital

    Chengdu, Sichuan, 610051, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Peking University Shenzhen Hospital

    Shenzhen, Guangdong, 518036, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • People's Hospital of Hunan Province

    Changsha, Hunan, 410005, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shanghai General Hospital

    Shanghai, Shanghai Municipality, 200080, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shanghai Pulmonary Hospital

    Shanghai, Shanghai Municipality, 200433, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sichuan Provincial People's Hospital

    Chengdu, Sichuan, 610072, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Fifth Affiliated Hospital of Zhengzhou University

    Zhengzhou, Henan, 450052, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Fifth Affiliated Hospital, Sun Yat-sen University

    Zhuhai, Guangdong, 519000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Bengbu Medical College

    Bengbu, Anhui, 233000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Chongqing Medical University

    Chongqing, Chongqing Municipality, 400016, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Xi'an Jiao Tong University

    Xi'an, Shaanxi, 710000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Clinical College of Guangzhou Medical University

    Guangzhou, Guangdong, 510120, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Second Affiliated Hospital of Zhengzhou University

    Zhengzhou, Henan, 450052, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Second Hospital Of Hebei Medical University

    Shijiazhuang, Hebei, 050000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tianjin First Central Hospital

    Tianjin, Tianjin Municipality, 300191, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tianjin Medical University General Hospital

    Tianjin, Tianjin Municipality, 300052, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xi'an Chest Hospital

    Xi'an, Shaanxi, 710100, China

  • Xiangya Hospital of Central South University

    Changsha, Hunan, 410000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Yan'an University Xianyang Hospital

    Xianyang, Shaanxi, 712000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Zhengzhou Central Hospital

    Zhengzhou, Henan, 450007, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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