New hope for Tough-to-Treat blood cancer: drug combo trial shows promise

NCT ID NCT04182204

Completed Disease control Sponsor: Hoffmann-La Roche Source: ClinicalTrials.gov ↗

Summary

This study tested whether adding a targeted drug called polatuzumab vedotin to a standard chemotherapy combination (R-GemOx) could help people with an aggressive type of lymphoma that had come back or stopped responding to prior treatments. It involved 270 adults whose cancer had relapsed or was refractory. The main goal was to see if the new combination helped patients live longer compared to the standard treatment alone.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

Abdurrahman Yurtarslan Onkoloji Training and Research Hospital

Ankara, 06200, Turkey (Türkiye)
Akdeniz Uni School of Medicine

Antalya, 07059, Turkey (Türkiye)
All India Institute of Medical Sciences ,Institute Rotary Cancer Hospital

New Delhi, National Capital Territory of Delhi, 110029, India
Amerikan HAstanesi Onkoloji Birimi Te?vikiye

Ni?anta??, 34365, Turkey (Türkiye)
Attiko Hospital

Athens, 124 62, Greece
Az. Osp. Uni Ria Policlinico Tor Vergata

Rome, Lazio, 00133, Italy
Azienda Ospedaliero-Universitaria Policlinico di Modena Ematologia

Modena, Emilia-Romagna, 41123, Italy
Cancer Center, Sun Yat-sen University of Medical Sciences

Guangzhou, 510060, China
Cancer Specialists

Jacksonville, Florida, 32256, United States
Centre Henri Becquerel

Rouen, 76038, France
Centre hospitalier regional de Trois-Rivieres

Trois-Rivières, Quebec, G8Z 3R9, Canada
Chungnam National University Hospital

Daejeon, 35015, South Korea
First Affiliated Hospital of Medical College of Xi'an Jiaotong University

Xi'an, 710061, China
Guangxi Cancer Hospital of Guangxi Medical University

Nanning, 530021, China
Gyeongsang National University Hospital

Gyeongsangnam-do, 52727, South Korea
Health Pharma Professional Research

Mexico City, Mexico CITY (federal District), 03100, Mexico
Hopital Bretonneau

Tours, 37044, France
Hopital De Haut Leveque

Pessac, 33604, France
Hopital Henri Mondor

Créteil, 94010, France
Hospital Clinico Universitario de Salamanca

Salamanca, 37007, Spain
Hospital Sao Rafael - HSR

Salvador, Estado de Bahia, 41253-190, Brazil
Hospital Univ. 12 de Octubre

Madrid, 28041, Spain
Hospital Universitari Germans Trias i Pujol

Badalona, Barcelona, 08915, Spain
Hospital Universitario Dr. Peset

Valencia, 46017, Spain
Hospital Universitario de Canarias

San Cristóbal de La Laguna, Tenerife, 38320, Spain
Hospital das Clinicas - FMUSP

São Paulo, São Paulo, 05403-000, Brazil
Hospital das Clinicas - UFRGS

Porto Alegre, Rio Grande do Sul, DUMMY_VALUE, Brazil
Hospital de Especialidades Centro Medico Nacional La Raza

Mexico City, Mexico CITY (federal District), 02990, Mexico
Hu Nan Provincial Cancer Hospital

Changsha, 410006, China
ICANS

Strasbourg, 67200, France
IHA Hematology Oncology Consultants - Ann Arbor

Ann Arbor, Michigan, 48106, United States
Institute of Hematology and Hospital of Blood Disease

Tianjin, 300020, China
Instituto Nacional de Cancerologia

Distrito Federal, 14080, Mexico
Istanbul Uni Istanbul Medical Faculty

Istanbul, 34093, Turkey (Türkiye)
Istanbul University Cerrahpasa Medical Faculty

Istanbul, 34098, Turkey (Türkiye)
Kings College Hospital

London, SE5 9RS, United Kingdom
Kocaeli Universitesi Tip Fakultesi

Kocaeli, 41380, Turkey (Türkiye)
Laiko General Hospital

Athens, 115 27, Greece
Liga Norte Riograndense Contra O Câncer

Natal, Rio Grande do Norte, 59040150, Brazil
London Health Sciences Centre

London, Ontario, N6A 5W9, Canada
MSKCC at Basking Ridge

Basking Ridge, New Jersey, 07920, United States
Memorial Cancer Institute at Memorial West

Pembroke Pines, Florida, 33028, United States
Memorial Sloan Kettering Cancer Center at Bergen

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Nassau

Uniondale, New York, 11553, United States
Memorial Sloan-Kettering Cancer Center

New York, New York, 10065, United States
Niagara Health Systems - St. Catherines General Site

St. Catharines, Ontario, L2R 7C6, Canada
Nottingham City Hospital

Nottingham, NG5 1PB, United Kingdom
Oulu University Hospital

Oulu, 90029, Finland
Pusan National University Hospital

Busan, 49241, South Korea
Sakarya Universitesi Egitim ve Arastirma Hastanesi

Adapazari/Sakarya, 54100, Turkey (Türkiye)
Seoul National University Bundang Hospital

Seongnam-si, 13605, South Korea
Severance Hospital, Yonsei University Health System

Seoul, 03722, South Korea
St James' Hospital

Dublin, DUMMY_VALUE, Ireland
Tampere University Hospital

Tampere, 33520, Finland
Tata Medical Center

Kolkata, West Bengal, 700160, India
Tata Memorial Hospital

Mumbai, Maharashtra, 400013, India
The 1st Affiliated Hospital of Nanchang Unversity

Nanchang, 330006, China
USL 4 di Prato - Nuovo Ospeale di Prato

Prato, Tuscany, 59100, Italy
Uni Degli Studi Di Bari, Policlinico

Bari, Apulia, 70124, Italy
Union Hospital Tongji Medical College Huazhong University of Science and Technology

Wuhan, 430023, China
Universitätsklinikum Ulm

Ulm, 89081, Germany
West China Hospital - Sichuan University

Chengdu, 610047, China

Conditions

Explore the condition pages connected to this study.

DIFFUSE LARGE B-CELL LYMPHOMA