New hope for elderly lymphoma patients: triple-drug combo targets aggressive cancer

NCT ID NCT07415980

First seen Feb 19, 2026 · Last updated May 08, 2026 · Updated 13 times

Summary

This study tests a three-drug combination (polatuzumab vedotin, rituximab, and chidamide) in older adults (70+ or frail 60-69) with a specific type of aggressive lymphoma called double-expressor DLBCL. The goal is to see if the combo is safe and effective at shrinking tumors. About 68 participants will receive the treatment, and researchers will monitor side effects and cancer response.

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