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A simple blood test may flag who faces higher risk after cancer surgery

NCT ID NCT07794722

Knowledge-focused Sponsor: Kocaeli City Hospital Source: ClinicalTrials.gov ↗

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Not yet recruiting
Registered, but not yet taking participants.
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The trial has finished. Results may not be published yet.
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Cancelled before anyone took part.

Expanded access (not trials)

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Approved
The treatment has been approved, so it is available normally rather than through this programme.

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Status unknown
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First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time

Summary

Researchers are testing whether a simple score called the Prognostic Nutritional Index (PNI) can predict complications and death within 30 and 90 days after cancer surgery. PNI is calculated from two routine blood values: albumin and lymphocyte count, which reflect a patient's nutritional and immune status. The study will review records of 1,500 adults who had oncologic surgery at Kocaeli City Hospital. If PNI proves useful, it could help doctors identify higher-risk patients before surgery and plan extra support.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If PNI proves reliable, doctors could use a simple blood test to identify patients at higher risk after cancer surgery, allowing earlier support and closer monitoring.
What could go wrong
This is a retrospective study, so it can show links but not prove cause and effect. The results may not apply to all patients or surgical types, and the score might not be accurate enough for routine use.

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Study facts

What this study's own registry entry says, in plain language.

Participants

1,500 people

The number who actually took part.

Started

Mar 2026

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All patients who met the inclusion criteria, were not excluded according to the exclusion criteria, and underwent oncologic surgery between the opening date of our hospital and the date of ethics committee approval will be included in the study.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Kocaeli City Hospital, all patients over 18 years old who have undergone oncologic surgery Exclusion Criteria: * Patients under 18 years of age * Patients with a history of bone marrow suppression or hematologic malignancy * Patients admitted as emergency cases * Patients who received albumin replacement within 1 month prior to surgery (preoperative period) * Patients who received chemotherapy/radiotherapy within the last 1 year * Patients who received immunosuppressive therapy within the last 1 year * Patients who received blood or blood product replacement within 1 month prior to surgery (preoperative period)

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Prognostic nutritional index

Contacts and locations

Locations

  • Kocaeli Şehir Hastanesi

    Kocaeli, Izmit, 41060, Turkey (Türkiye)

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