Scientists investigate the roots of severe PMS in over 1,500 women
NCT ID NCT00001177
First seen Nov 01, 2025 · Last updated Jun 04, 2026 · Updated 32 times
Summary
This study aimed to better understand premenstrual syndrome (PMS) and its severe form, PMDD, by evaluating over 1,500 women. Participants completed interviews, mood ratings, and hormone tests to identify what causes mood changes before menstruation. A subgroup with severe symptoms also joined studies on possible treatments and genetic factors. The goal was to describe symptoms and find biological clues, not to test a new treatment.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
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