First human trial launches for new cancer pill targeting specific genetic weakness
NCT ID NCT07284186
Summary
This is the first study in people testing a new oral drug called PLX-61639 for advanced solid tumors that have a specific genetic change (SMARCA4 mutation) and have stopped responding to standard treatments. The main goals are to find a safe dose and see if the drug shows early signs of fighting the cancer. About 155 participants with certain advanced cancers, like lung or stomach cancer, will take a daily pill for as long as it helps control their disease.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Research Site
RECRUITINGScottsdale, Arizona, 85258, United States
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Research Site
NOT_YET_RECRUITINGDuarte, California, 91010, United States
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Research Site
NOT_YET_RECRUITINGOrange, California, 92868, United States
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Research Site
NOT_YET_RECRUITINGBoston, Massachusetts, 02114, United States
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Research Site
RECRUITINGSt Louis, Missouri, 63110, United States
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Research Site
NOT_YET_RECRUITINGNew York, New York, 10044, United States
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Research Site
RECRUITINGDurham, North Carolina, 27710, United States
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Research Site
RECRUITINGCleveland, Ohio, 44106, United States
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Research Site
RECRUITINGSan Antonio, Texas, 78229, United States
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Research Site
RECRUITINGFairfax, Virginia, 22031, United States
Conditions
Explore the condition pages connected to this study.