New drug targets Hard-to-Treat cancers with specific gene flaw
NCT ID NCT07284186
First seen Dec 17, 2025 · Last updated May 16, 2026 · Updated 23 times
Summary
This study tests a new drug called PLX-61639 in adults with advanced solid tumors that have a specific genetic change (SMARCA4 mutation) and have stopped responding to standard treatments. The drug is taken daily by mouth and aims to shrink or control the cancer. The trial will enroll about 155 people to find the safest dose and see if the drug works.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Research Site
RECRUITINGScottsdale, Arizona, 85258, United States
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Research Site
NOT_YET_RECRUITINGDuarte, California, 91010, United States
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Research Site
NOT_YET_RECRUITINGOrange, California, 92868, United States
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Research Site
NOT_YET_RECRUITINGBoston, Massachusetts, 02114, United States
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Research Site
RECRUITINGSt Louis, Missouri, 63110, United States
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Research Site
RECRUITINGNew York, New York, 10044, United States
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Research Site
RECRUITINGDurham, North Carolina, 27710, United States
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Research Site
RECRUITINGCleveland, Ohio, 44106, United States
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Research Site
RECRUITINGSan Antonio, Texas, 78229, United States
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Research Site
RECRUITINGFairfax, Virginia, 22031, United States
Conditions
Explore the condition pages connected to this study.