New shot could slash pancreatitis risk for those with Sky-High fats in blood

NCT ID NCT06880770

Recruiting now Disease control Sponsor: Arrowhead Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 29 times

Summary

This study tests a drug called plozasiran in about 288 adults with severely high triglycerides who have had pancreatitis attacks. Participants get either the drug or a placebo every three months. The goal is to see if the drug can prevent future pancreatitis episodes and lower fat levels in the blood.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Clinical Research Site 1
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Mesquite, Texas, 75149, United States
Clinical Research Site 2
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San Antonio, Texas, 78233, United States
Clinical Research Site 3
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Greensboro, North Carolina, 27401, United States
Clinical Research Site 4
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Santa Clarita, California, 91321, United States
Clinical Research Site 5
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North Platte, Nebraska, 69101, United States
Clinical Research Site 6
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Springfield, Illinois, 62702, United States
Clinical Research Site 7
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Philadelphia, Pennsylvania, 19107, United States
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Plovdiv, 4002, Bulgaria
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Beijing, Beijing Municipality, 100730, China
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Baotou, Inner Mongolia, 014010, China
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Nanchang, Jiangxi, 330006, China
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Shanghai, Shanghai Municipality, 201620, China
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Hangzhou, Zhejiang, 310000, China
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Amman, 11821, Jordan
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Irbid, 21166, Jordan
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Irbid, 22110, Jordan
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Belgrade, 11000, Serbia
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Zaječar, 19000, Serbia
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Gothenburg, 41345, Sweden
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Stockholm, 14186, Sweden
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Los Angeles, California, 90027, United States
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New Haven, Connecticut, 06519, United States
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Indianapolis, Indiana, 46202, United States
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Kansas City, Kansas, 66160, United States
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Ann Arbor, Michigan, 48109, United States
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St Louis, Missouri, 63110, United States
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Wilmington, North Carolina, 28412, United States
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Pittsburgh, Pennsylvania, 15213, United States
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Seattle, Washington, 98109, United States
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Ramos Mejía, Buenos Aires, 1704, Argentina
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Córdoba, Córdoba Province, 5000, Argentina
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Córdoba, Córdoba Province, X5003DCE, Argentina
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Rosario, Santa Fe Province, 2000, Argentina
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Ciudad Autonoma Buenos Aires, C1430CKE, Argentina
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Graz, 8036, Austria
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Fortaleza, Ceará, 60430-370, Brazil
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Belo Horizonte, Minas Gerais, 30150-274, Brazil
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Belo Horizonte, Minas Gerais, 30150-320, Brazil
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Belo Horizonte, Minas Gerais, 30220-140, Brazil
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Porto Alegre, Rio Grande do Sul, 90035-903, Brazil
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Pôrto Alegre, Rio Grande do Sul, 90050-170, Brazil
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São Paulo, São Paulo, 05403-900, Brazil
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Burgas, 8000, Bulgaria
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Pleven, 5800, Bulgaria
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Plovdiv, 4003, Bulgaria
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Rousse, 7013, Bulgaria
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Sofia, 1404, Bulgaria
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Sofia, 1431, Bulgaria
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Stara Zagora, 6000, Bulgaria
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Guiyang, Guizhou, 550000, China
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Harbin, Heilongjiang, 150040, China
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Chifeng, Inner Mongolia, 024099, China
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Chengdu, Sichuan, 610041, China
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Hangzhou, Zhejiang, 310003, China
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Beijing, 100053, China
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Nanjing, 210002, China
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Barranquilla, 080020, Colombia
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Cali, 760042, Colombia
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Puerto Colombia, 081007, Colombia
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Budapest, 1083, Hungary
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Budapest, 1132, Hungary
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Szeged, 6725, Hungary
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Amman, 11190, Jordan
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Amman, 11942, Jordan
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Guadalajara, Jalisco, 44670, Mexico
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Mexico City, Mexico City, 06700, Mexico
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Muscat, 123, Oman
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Riyadh, 11211, Saudi Arabia
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Riyadh, 11426, Saudi Arabia
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Riyadh, 11472, Saudi Arabia
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Belgrade, 11000, Serbia
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Pančevo, 26000, Serbia
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Seongnam-si, Gyeonggi-do, 13620, South Korea
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Jeonju, Jeollabuk-do, 54907, South Korea
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Busan, 49201, South Korea
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Sejong, 30099, South Korea
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Seoul, 02841, South Korea
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Seoul, 05505, South Korea
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Seoul, 06351, South Korea
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Seoul, 06591, South Korea
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Abu Dhabi, 133500, United Arab Emirates
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Abu Dhabi, 51900, United Arab Emirates
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Al Ain City, 15258, United Arab Emirates

Conditions

Explore the condition pages connected to this study.

SEVERE HYPERTRIGLYCERIDEMIA