New drug offers hope for rare, severe high triglyceride conditions
NCT ID NCT06796426
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This program gives adults and adolescents with familial chylomicronemia syndrome (FCS) and adults with severe hypertriglyceridemia (SHTG) access to an experimental drug called plozasiran. Participants receive injections every 3 months for 15 to 21 months. The goal is to lower dangerously high triglyceride levels that standard treatments haven't controlled.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- plozasiran (a drug injection)
- What this could lead to
- If it works, this could provide a treatment option for people with severe high triglycerides who haven't responded to standard therapy.
- What could go wrong
- This is an expanded access program, not a controlled trial, so results are less certain. The drug may not work for everyone and could have side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Arrowhead Pharmaceuticals, Inc.
AVAILABLEPasadena, California, 91105, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.