Blood gel may speed nasal surgery recovery
NCT ID NCT07645053
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether a gel made from a patient's own blood, called platelet-rich fibrin (PRF), could help the nose heal better after surgery. Fourteen adults having nasal surgery had PRF applied to one side of their nose, while the other side was left untreated. Researchers checked for crusting and bleeding one week and one month later. The goal was to see if PRF reduces discomfort and speeds up recovery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Platelet-rich fibrin (PRF) — a gel made from the patient's own blood, applied to the surgical site to promote healing.
- What this could lead to
- If it works, this could lead to a simple, low-cost way to improve recovery after nasal surgery, reducing crusting and bleeding.
- What could go wrong
- This is a very small, early-phase study with only 14 participants. Results may not apply to everyone, and the benefits might not be significant.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 1/2
Runs two stages together: safety and dose first, then whether the treatment works.
- Participants
-
14 people
The number who actually took part.
- Started
-
Jun 2024
- Finished
-
Oct 2024
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 years or older. Patients undergoing sinonasal surgery including partial inferior turbinectomy at the Centro de Otorrinolaringologia e Fonoaudiologia de São Paulo (COF). Ability to provide written informed consent. Willingness to attend scheduled postoperative follow-up visits at 1 week and 1 month after surgery. Exclusion Criteria: * Refusal or inability to provide written informed consent. Failure to attend either the 1-week or the 1-month postoperative follow-up visit. Incomplete postoperative evaluation data.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hospital Edmundo Vasconcelos
São Paulo, São Paulo, 04038-905, Brazil
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