New plague vaccine enters human testing

NCT ID NCT07207408

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new vaccine called rF1V-1018 to prevent pneumonic plague, a severe lung infection spread by aerosol. Researchers will give the vaccine to 148 healthy adults aged 18 to 55 to check if it triggers a strong immune response and is safe. The goal is to find the best dose and schedule for future larger trials.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

rF1V-1018 vaccine

What this could lead to

If successful, this could lead to a vaccine that protects people from pneumonic plague, a rare but deadly lung infection caused by Yersinia pestis.

What could go wrong

This is an early Phase 2 trial with only 148 participants, so results may not apply to everyone. The vaccine may not produce strong enough immunity or could have side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • 103

    ACTIVE_NOT_RECRUITING

    Miami, Florida, 33172, United States

  • AMR- El Dorado

    ACTIVE_NOT_RECRUITING

    El Dorado, Kansas, 67042, United States

  • AMR- Las Vegas

    ACTIVE_NOT_RECRUITING

    Las Vegas, Nevada, 889119, United States

  • CTI Clinical Research Center

    RECRUITING

    Cincinnati, Ohio, 45212, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••