New PKU drink tried in kids: will they drink it?
NCT ID NCT05995717
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a special drink called PKU UP in 16 children with phenylketonuria (PKU) aged 1 to 10 years. The drink is designed to replace some of the protein they need while keeping their phenylalanine levels safe. Researchers checked how well the children tolerated the drink, whether they liked it, and if it helped control their condition over 26 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
PKU UP (a special medical food drink for managing PKU)
What this could lead to
If this product is well-tolerated, it could offer a more convenient and palatable dietary option for children with PKU, helping them stick to their diet and maintain better metabolic control.
What could go wrong
This was a small, single-arm study with only 16 children, so results may not apply to everyone. It tested acceptability, not long-term health outcomes, and the product may still cause gastrointestinal issues or be refused by some children.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Birmingham Children's Hospital
Birmingham, B4 6NH, United Kingdom
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Great Ormond Street Hospital for Children NHS Foundation Trust
London, WC1N 3JH, United Kingdom
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Nottingham Children's Hospital
Nottingham, NG7 2UH, United Kingdom
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Royal Belfast Hospital for Sick Children
Belfast, BT12 6BE, United Kingdom
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Sheffield Children's Hospital
Sheffield, S10 2TH, United Kingdom
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St. Luke's Hospital
Bradford, BD5 0NA, United Kingdom
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University Hospitals Bristol and Weston NHS Foundation Trust
Bristol, BS2 8BJ, United Kingdom