New approach aims to boost effectiveness of PKU drug
NCT ID NCT07477691
Summary
This study is testing whether adding a medication called methotrexate to the existing PKU treatment Palynziq can help control the condition better. It aims to see if methotrexate reduces the body's immune reaction to Palynziq, potentially making the treatment more tolerable and effective at lowering harmful phenylalanine levels. The study will include about 12 adults with PKU who either have not tried Palynziq or are already taking it but need better control.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Ann & Robert H. Lurie Children's Hospital of Chicago
Chicago, Illinois, 60611, United States
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Children's Hospital of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Indiana University School of Medicine
Indianapolis, Indiana, 46202, United States
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Oregon Health & Science University (OHSU) - PARENT
Portland, Oregon, 97239, United States
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UCLA Dept. of Human Genetics
Los Angeles, California, 90095, United States
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UT Southwestern Medical Center
Dallas, Texas, 75390, United States
Contact
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University Of South Florida Medical Center
Tampa, Florida, 33613, United States
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University of Minnesota Medical School
Minneapolis, Minnesota, 55455, United States
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University of Pittsburgh Medical Center (UPMC) - Children's Hospital of Pittsburgh
Philadelphia, Pennsylvania, 19104, United States
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University of Rochester Medical Center (URMC)
Rochester, New York, 14642, United States
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University of Utah Hospital
Salt Lake City, Utah, 84108, United States
Conditions
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