Gene study seeks clues to why sickle cell symptoms differ
NCT ID NCT03685721
First seen Oct 31, 2025 · Last updated May 25, 2026 · Updated 31 times
Summary
This study looks at how small differences in a gene called PKLR might affect red blood cell function and symptoms in people with sickle cell disease. Researchers will collect blood samples from 800 adults of African descent, both with and without sickle cell disease, to analyze genetic variants and related proteins. The goal is to better understand why some people have more severe symptoms than others.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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