New drug cocktail targets tough leukemia in early trial

NCT ID NCT01861314

First seen Oct 31, 2025 · Last updated Apr 30, 2026 · Updated 24 times

Summary

This early-phase study tests a combination of three drugs—bortezomib, sorafenib, and decitabine—in patients with acute myeloid leukemia (AML), especially those who are older or whose cancer has returned. The main goal is to find the safest dose and understand side effects. The study enrolls 15 participants and is no longer recruiting new patients.

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Contacts and locations

Locations

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

Conditions

Explore the condition pages connected to this study.