New pill takes on Hard-to-Treat prostate cancer by targeting a key enzyme and boosting immunity

NCT ID NCT06705686

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 27 times

Summary

This study tests a new daily pill, (R)-9bMS, for men with metastatic castration-resistant prostate cancer (mCRPC) whose cancer has stopped responding to standard hormone treatments. The drug works by blocking a protein called ACK1 and also helps the immune system fight the tumor. About 40 participants will take the drug twice daily for up to 12 cycles to find the safest dose and see if it can shrink tumors or slow the disease.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Wisconsin Carbone Cancer Center (UWCCC) - Cancer Connect

    RECRUITING

    Madison, Wisconsin, 53792, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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