New Imaging-Enhanced CAR T-Cell therapy targets Hard-to-Treat lymphoma

NCT ID NCT07343934

First seen Jan 26, 2026 · Last updated Jun 04, 2026 · Updated 20 times

Summary

This early-phase study tests a new type of CAR T-cell therapy (huCART19-IL18-eDHFR) in 6 adults with follicular lymphoma that has returned or not responded to at least two prior treatments. The therapy uses a special imaging tag to track the cells in the body via PET/CT scans. The main goals are to check safety and see if the cells can be detected, while also looking at how well they work against the cancer.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for RELAPSED OR REFRACTORY FOLLICULAR LYMPHOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.