Virus vs. superbug: inhaled phage therapy fights stubborn lung infection
NCT ID NCT05616221
Summary
This study tested whether inhaling a special virus mixture (called AP-PA02) could safely reduce a hard-to-treat bacteria in the lungs of people with bronchiectasis. It involved 48 adults with a chronic Pseudomonas aeruginosa infection. Participants were randomly assigned to receive either the active treatment or a placebo to compare safety and effectiveness.
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Contacts and locations
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Locations
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Georgetown University Hospital / Pulmonary Critical Care and Sleep Medicine
Washington D.C., District of Columbia, 20007, United States
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Johns Hopkins University School of Medicine
Baltimore, Maryland, 21224, United States
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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Mayo Clinic/Pulmonary, Critical Care, and Sleep Medicine
Jacksonville, Florida, 32224, United States
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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New York Medical College
Hawthorne, New York, 10595, United States
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Oregon Health & Science University
Portland, Oregon, 97239, United States
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Rutgers Robert Wood Johnson Medical School
New Brunswick, New Jersey, 08901, United States
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Southern California Institute for Respiratory Diseases Cedars-Sinai West Tower
Los Angeles, California, 90048, United States
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Southwest General Healthcare Center
Fort Myers, Florida, 33907, United States
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St. Lukes Hospital
Boise, Idaho, 83702, United States
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TecTum Medical Research, Inc.
Hollywood, Florida, 33024, United States
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The University of Kansas Medical Center / Dept of Medicine
Kansas City, Kansas, 66160, United States
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UCONN Health
Farmington, Connecticut, 06030, United States
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University Hospitals of Cleveland Medical Center
Cleveland, Ohio, 44106, United States
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University of Cincinnati - College of Medicine
Cincinnati, Ohio, 45267, United States
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University of Miami
Miami, Florida, 33146, United States
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University of Pennslyvania
Philadelphia, Pennsylvania, 19104, United States
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University of Texas Health Science Center at Tyler
Tyler, Texas, 75708, United States
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University of Washington Medical Center
Seattle, Washington, 98195, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37203, United States
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Velocity Clinical Research
Mobile, Alabama, 36608, United States
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Virginia Commonwealth University (VCU)
Richmond, Virginia, 23298, United States
Conditions
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