New combo therapy aims to tame aggressive leukemia with less toxicity
NCT ID NCT07493161
First seen Apr 06, 2026 · Last updated May 20, 2026 · Updated 8 times
Summary
This study tests a new treatment for adults newly diagnosed with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL), a fast-growing blood cancer. It combines low-intensity chemotherapy with targeted drugs (venetoclax, blinatumomab, and olverembatinib) to improve remission and survival while reducing side effects. About 110 participants will be randomly assigned to receive venetoclax or not during the first three treatment cycles. The goal is to see if this approach leads to better disease control and longer event-free survival.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Blood Diseases Hospital
RECRUITINGTianjin, Tianjin Municipality, 300020, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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