New combo aims to wipe out hidden leukemia before transplant

NCT ID NCT07443488

First seen Mar 10, 2026 · Last updated May 13, 2026 · Updated 10 times

Summary

This study tests whether a combination of two drugs (olverembatinib and inotuzumab ozogamicin) can eliminate leftover leukemia cells in adults with a certain type of acute lymphoblastic leukemia (Ph+ ALL) who still have detectable disease after initial treatment. The goal is to achieve a deep remission before proceeding to a stem cell transplant. About 20 participants will be enrolled in this phase 2 trial.

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