No-Needle dental numbing: does pH tweak boost pain relief?

NCT ID NCT07318311

First seen Jan 07, 2026 · Last updated May 08, 2026 · Updated 22 times

Summary

This study looked at whether adjusting the pH (acidity level) of a common numbing medicine (articaine with epinephrine) improves its effectiveness when given through a needle-free jet injector. Forty-five healthy adults received the treatment, and researchers measured how well it numbed the tooth. The goal was to see if this simple change could make dental procedures more comfortable without using needles.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for COMPARATIVE EVALUATION OF THE EFFECT OF PH ADJUSTMENT OF THE SOLUTION OF ARTICAINE WITH EPINEPHRINE ON THE EFFICACY OF JET ANESTHESIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Dental School Aristotle University of Thessaloniki

    Thessaloniki, 54124, Greece

Conditions

Explore the condition pages connected to this study.