Sugar therapy trial targets rare genetic disease

NCT ID NCT05402332

First seen Nov 01, 2025 · Last updated May 02, 2026 · Updated 27 times

Summary

This study tests a sugar called D-galactose (AVTX-801) in 8 adults with PGM1-CDG, a rare inherited disorder that affects how the body makes proteins. Participants must already be taking D-galactose. The trial aims to see if the treatment reduces episodes of low blood sugar, liver stress, or blood clotting problems. It is a placebo-controlled crossover study, meaning each person will receive both the drug and a placebo at different times.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mayo Clinic Rochester

    Rochester, Minnesota, 55905, United States

Conditions

Explore the condition pages connected to this study.