New bladder cancer drug combo shows promise in early trial

NCT ID NCT07206225

First seen Oct 31, 2025 · Last updated May 12, 2026 · Updated 25 times

Summary

This early-stage study tests a new drug, PF-08052667, for adults with a type of bladder cancer that hasn't spread into the bladder muscle but is likely to return. The drug is given alone or with standard treatments like BCG and/or sasanlimab. The goal is to check safety and find the best dose. About 294 people will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AUC Urologists, LLC

    RECRUITING

    Myrtle Beach, South Carolina, 29572, United States

  • AdventHealth Orlando

    NOT_YET_RECRUITING

    Orlando, Florida, 32803, United States

  • Baptist M&S Imaging (Medical Center)

    RECRUITING

    San Antonio, Texas, 78229, United States

  • Biorepository and Precision Pathology Center (BRPC)

    RECRUITING

    Durham, North Carolina, 27710, United States

  • Carolina Urologic Research Center, LLC

    RECRUITING

    Myrtle Beach, South Carolina, 29572, United States

  • Coastal Eye Group

    RECRUITING

    Myrtle Beach, South Carolina, 29579, United States

  • Duke Cancer Institute

    RECRUITING

    Durham, North Carolina, 27710, United States

  • Emory University

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Emory University Hospital

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Emory University Hospital Midtown

    RECRUITING

    Atlanta, Georgia, 30308, United States

  • Grand Strand Medical Center

    RECRUITING

    Myrtle Beach, South Carolina, 295724607, United States

  • Gustave Roussy

    NOT_YET_RECRUITING

    Villejuif, VAL DE Marne, 94800, France

  • Hadassah Medical Center

    RECRUITING

    Jerusalem, Jerusalem, 9112001, Israel

  • Hospital Universitario 12 de Octubre

    RECRUITING

    Madrid, 28041, Spain

  • Icahn School of Medicine at Mount Sinai

    NOT_YET_RECRUITING

    New York, New York, 10029, United States

  • MCOA Eye Associates

    RECRUITING

    San Antonio, Texas, 78240, United States

  • Moffitt Cancer Center

    NOT_YET_RECRUITING

    Tampa, Florida, 33612, United States

  • Moffitt Cancer Center - International Plaza

    NOT_YET_RECRUITING

    Tampa, Florida, 33607, United States

  • Moffitt Cancer Center - McKinley Campus

    NOT_YET_RECRUITING

    Tampa, Florida, 33612, United States

  • Moffitt Cancer Center at SouthShore

    NOT_YET_RECRUITING

    Ruskin, Florida, 33570, United States

  • Moffitt Cancer Center at Wesley Chapel

    NOT_YET_RECRUITING

    Wesley Chapel, Florida, 33544, United States

  • Moffitt McKinley Hospital

    NOT_YET_RECRUITING

    Tampa, Florida, 33612, United States

  • Northwestern Memorial Hospital

    NOT_YET_RECRUITING

    Chicago, Illinois, 60611, United States

  • Northwestern University - Feinberg School of Medicine

    NOT_YET_RECRUITING

    Chicago, Illinois, 60611, United States

  • Parkway Surgery Center

    RECRUITING

    Myrtle Beach, South Carolina, 29572, United States

  • Rabin Medical Center

    RECRUITING

    Petah Tikva, Central District, 4941492, Israel

  • SUNY Upstate Medical University

    NOT_YET_RECRUITING

    Syracuse, New York, 13210, United States

  • SUNY Upstate Medical University-Community Campus

    NOT_YET_RECRUITING

    Syracuse, New York, 13215, United States

  • Samsung Medical Center

    NOT_YET_RECRUITING

    Seoul, Seoul Teukbyeolsi [seoul], 06351, South Korea

  • Seoul National University Hospital

    NOT_YET_RECRUITING

    Seoul, Seoul-teukbyeolsi [seoul], 03080, South Korea

  • Severance Hospital, Yonsei University Health System

    NOT_YET_RECRUITING

    Seoul, Seoul-teukbyeolsi, 03722, South Korea

  • Sheba Medical Center

    RECRUITING

    Ramat Gan, Central District, 5265601, Israel

  • Substrate Services Core Research Support (SSCRS)

    RECRUITING

    Durham, North Carolina, 27710, United States

  • The University of Kansas - Clinical Research Center

    RECRUITING

    Fairway, Kansas, 66205, United States

  • The University of Kansas Cancer Center - Westwood

    RECRUITING

    Westwood, Kansas, 66205, United States

  • The University of Kansas Hospital

    RECRUITING

    Kansas City, Kansas, 66160, United States

  • The University of Kansas Hospital - Indian Creek Campus

    RECRUITING

    Overland Park, Kansas, 66211, United States

  • The University of Kansas Hospital Cambridge North Tower A

    RECRUITING

    Kansas City, Kansas, 66160, United States

  • The University of Kansas Medical Center Medical Office Building

    RECRUITING

    Kansas City, Kansas, 66160, United States

  • USA Clinical Trials

    RECRUITING

    San Antonio, Texas, 78229, United States

  • UT Southwestern Medical Center

    NOT_YET_RECRUITING

    Dallas, Texas, 75390, United States

  • University of Alabama at Birmingham

    NOT_YET_RECRUITING

    Birmingham, Alabama, 35233, United States

  • University of Alabama at Birmingham

    NOT_YET_RECRUITING

    Birmingham, Alabama, 35249, United States

  • University of Alabama at Birmingham

    NOT_YET_RECRUITING

    Birmingham, Alabama, 35294, United States

  • University of Iowa Health Care

    NOT_YET_RECRUITING

    Iowa City, Iowa, 52242, United States

  • Upstate Specialty Services at Harrison Center

    NOT_YET_RECRUITING

    Syracuse, New York, 13202, United States

  • Urology Associates, P.C.

    RECRUITING

    Nashville, Tennessee, 37209, United States

Conditions

Explore the condition pages connected to this study.