New drug shrinks rare joint tumors in patients who can't have surgery
NCT ID NCT04488822
First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 29 times
Summary
This study tests a drug called pexidartinib in 40 adults with a rare, non-cancerous joint tumor (tenosynovial giant cell tumor) that causes severe symptoms and can't be helped by surgery. The main goal is to see if the drug shrinks the tumor after 25 weeks of treatment. Participants take the drug by mouth and are monitored for safety and tumor response using MRI scans.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Beijing Ji Shui Tan Hospital
Beijing, China
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Fudan University Shanghai Cancer Center
Shanghai, China
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National Taiwan University Hospital
Taipei, Taiwan
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Peking University Cancer Hospital
Beijing, China
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Shanghai General Hospital
Shanghai, China
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Taipei Veterans General Hospital
Taipei, Taiwan
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The First Affiliated Hospital, Sun Yat-sen University
Guangzhou, China
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The Second Affiliated Hospital of Zhejiang University School of Medicine
Hangzhou, China
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Zhejiang Cancer Hospital
Hangzhou, China
Conditions
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