New hepatitis b drug studied in Liver-Impaired patients

NCT ID NCT07342868

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tests a single dose of the drug pevifoscorvir sodium in 16 adults: 8 with moderate liver impairment and 8 healthy volunteers. Researchers want to see how the drug is processed in the body and if it is safe. The goal is to gather information for future dosing recommendations in people with chronic hepatitis B.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

pevifoscorvir sodium (ALG-000184)

What this could lead to

If successful, this study could help determine safe dosing of pevifoscorvir sodium for chronic hepatitis B patients with liver problems.

What could go wrong

This is a very early Phase 1 trial with only 16 people. It focuses on how the drug moves through the body, not on curing disease. Results may not apply to broader populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic hepatitis B virus infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Orlando Clinical Research Center

    RECRUITING

    Orlando, Florida, 32809, United States

    Contact Email: •••••@•••••