Smart scans guide tailored therapy for hodgkin lymphoma patients

NCT ID NCT03233347

Ongoing Disease control Sponsor: Academic and Community Cancer Research United Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a personalized approach for people with early-stage Hodgkin lymphoma. Doctors use PET scans to decide if standard chemotherapy alone is enough or if adding immunotherapy drugs can improve results. The goal is to boost survival while limiting unnecessary treatment. About 82 participants will receive a combination of chemotherapy and immune-boosting drugs based on their scan results.

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Conditions

The condition(s) this trial relates to.

classic Hodgkin lymphoma Hodgkins lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANN ARBOR STAGE I HODGKIN LYMPHOMA ANN ARBOR STAGE IA HODGKIN LYMPHOMA ANN ARBOR STAGE IB HODGKIN LYMPHOMA ANN ARBOR STAGE II HODGKIN LYMPHOMA ANN ARBOR STAGE IIA HODGKIN LYMPHOMA ANN ARBOR STAGE IIB HODGKIN LYMPHOMA CLASSIC HODGKIN LYMPHOMA

Contacts and locations

Locations

Carolinas Medical Center/Levine Cancer Institute

Charlotte, North Carolina, 28203, United States
City of Hope Comprehensive Cancer Center

Duarte, California, 91010, United States
Hackensack University Medical Center

Hackensack, New Jersey, 07601, United States
M D Anderson Cancer Center

Houston, Texas, 77030, United States
Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States
University of Nebraska Medical Center

Omaha, Nebraska, 68198, United States
University of Pennsylvania/Abramson Cancer Center

Philadelphia, Pennsylvania, 19104, United States
University of Washington Medical Center - Montlake

Seattle, Washington, 98195, United States
Vanderbilt University/Ingram Cancer Center

Nashville, Tennessee, 37232, United States

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