PET scans reveal hidden leukemia spots that could impact CAR t success

NCT ID NCT05969002

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 21 times

Summary

This study tested whether a special PET scan (FDG PET-CT) can find leukemia that has spread outside the bone marrow in people with relapsed or hard-to-treat B-cell acute lymphoblastic leukemia. Ten participants, ages 5 to 39, received a PET scan before and after CAR T-cell therapy. The goal was to see how common these hidden spots are and whether they affect treatment success. The study did not offer a new treatment but aimed to improve how doctors monitor the disease.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.