Can a simple drug get your gut moving again after surgery?

NCT ID NCT05334485

First seen Jan 08, 2026 · Last updated Jun 13, 2026 · Updated 31 times

Summary

This study tests whether pyridostigmine, a medication, can safely help the bowel start working again after colon or rectal surgery. About 50 adults who develop a slow bowel (postoperative ileus) after surgery will receive either the drug or a placebo. The goal is to see if the drug speeds up passing gas and stool, and to monitor any side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for POSTOPERATIVE ILEUS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cleveland Clinic Main Campus

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.