Second dose of targeted combo shows promise for tough breast cancer

NCT ID NCT02514681

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 22 times

Summary

This study looked at whether giving pertuzumab again, along with trastuzumab and chemotherapy, helps people with advanced HER2-positive breast cancer live longer without their disease getting worse. About 226 adults who had already been treated with pertuzumab took part. The goal was to see if retreatment works better than just trastuzumab and chemo alone.

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Contacts and locations

Locations

  • Aichi Cancer Center

    Chikusa-ku, Aichi-ken, 4648681, Japan

  • Japan Breast Cancer Research Group

    Chuo-ku, Nihonbashi, Koami-cho, Tokyo, 1030016, Japan

  • Kumamoto University Hospital

    Kumamoto, Kumamoto, 8608556, Japan

Conditions

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