New whooping cough vaccine passes major safety check in thousands of adults

NCT ID NCT06798831

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This large Phase 3 trial is testing the safety of a new recombinant pertussis (whooping cough) vaccine in 2,399 healthy adults aged 18 to 75. Participants receive a single booster dose, and researchers monitor for side effects over 28 days. The goal is to confirm the vaccine is safe and consistent across different manufacturing lots.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Recombinant acellular pertussis (aP) vaccine (Pertagen®)

What this could lead to

If successful, this could provide a safer, well-tolerated whooping cough booster for adults, helping reduce spread and protect vulnerable populations.

What could go wrong

This is a safety-focused trial, not designed to prove effectiveness. Rare side effects may still emerge, and results may not apply to children or older adults.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pertussis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chula Clinical Research Center (Chula CRC)

    Bangkok, Bangkok, 10330, Thailand

  • Queen Saovabha Memorial Institute, Thai Red Cross Society

    Bangkok, Bangkok, 10330, Thailand

  • Thai Red Cross AIDS and Infectious Diseases Research Centre

    Bangkok, Bangkok, 10330, Thailand