Could your genes decide when you get a mammogram? major study tests personalized breast cancer screening

NCT ID NCT03672331

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study is testing whether a breast cancer screening plan based on each woman's personal risk (using clinical factors and genetic markers) works better than the standard schedule. Over 53,000 women aged 40-70 are being randomly assigned to either risk-based or standard screening for 4 years. The goal is to see if the personalized approach reduces the number of advanced (stage 2 or higher) breast cancers detected.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could show that tailoring screening to a woman's personal risk is better than a one-size-fits-all approach, potentially reducing advanced breast cancers.

What could go wrong

This is a large study, but results are not yet available. The personalized strategy may not prove superior, and risk assessment tools may not be accurate for all women.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AUSL Reggio Emilia

    Reggio Emilia, Emilia-Romagna, Italy

  • Assuta Medical Center Ramat HaHayal

    Tel Aviv, Israel

  • Cambridge University Hospitals NHS Foundation Trust

    Cambridge, Cambridgeshire, United Kingdom

  • Gustave roussy

    Villejuif, France

  • Institut Jules Bordet

    Brussels, Belgium

  • Marta Romản

    Barcelona, Spain