Blood test guides cancer treatment: trial aims to tweak therapy for better control

NCT ID NCT04604067

Summary

This trial is testing a more personalized approach to treating an aggressive blood cancer called diffuse large B-cell lymphoma (DLBCL). It aims to see if adjusting the standard treatment based on early results from PET scans and a special blood test (ctDNA) can improve outcomes. The study will test if adding a targeted drug helps some patients, and if reducing treatment is safe for others who respond well early on.

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Contacts and locations

Locations

  • Azienda Ospedaliera Universitaria Maggiore della Carita di Novara

    Novara, 20503, Italy

  • Centre Hospitalier Universitaire Vaudois

    Lausanne, CH-1011, Switzerland

  • City Hospital Triemli

    Zurich, CH-8063, Switzerland

  • Hopital Fribourgeois

    Fribourg, 1708, Switzerland

  • Hopitaux Universitaire de Genève (HUG)

    Geneva, 1211, Switzerland

  • Inselspital, Bern

    Bern, CH-3010, Switzerland

  • Istituto Oncologico della Svizzera Italiana

    Bellinzona, 6500, Switzerland

  • Kantonsspital Aarau

    Aarau, CH-5001, Switzerland

  • Kantonsspital Baden (Baden/Brugg)

    Baden, 5404, Switzerland

  • Kantonsspital Graubünden

    Chur, 7000, Switzerland

  • Kantonsspital Luzern

    Luzerne, CH-6000, Switzerland

  • Kantonsspital Olten

    Olten, CH-4600, Switzerland

  • Kantonsspital St. Gallen

    Sankt Gallen, 9007, Switzerland

  • Kantonsspital Winterthur

    Winterthur, 8401, Switzerland

  • Ospedale Papa Giovanni XXIII

    Bergamo, 24127, Italy

  • Policlinico Agostino Gemelli

    Roma, 00168, Italy

  • Réseau Hospitalier Neuchâtelois (RHNe)

    Neuchâtel, 2000, Switzerland

  • St. Claraspital

    Basel, 4058, Switzerland

  • UniversitätsSpital Zürich

    Zurich, 8091, Switzerland

Conditions

Explore the condition pages connected to this study.