Could custom blood pressure goals save more hearts?

NCT ID NCT07345559

Recruiting now Disease control Sponsor: CMC Ambroise Paré Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

Cardiogenic shock is a life-threatening condition where the heart can't pump enough blood. This study tests whether setting a personalized blood pressure target based on central venous pressure improves survival and reduces organ damage compared to the standard fixed target. About 400 adults in cardiogenic shock will be randomly assigned to either personalized or standard blood pressure management.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: personalized blood pressure management
What this could lead to: If successful, this could lead to a new standard for managing blood pressure in cardiogenic shock, potentially reducing deaths and organ failure.
What could go wrong: This is a mid-sized trial testing a strategy, not a new drug. The benefit may be small or not apply to all patients, and the approach requires invasive monitoring.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cardiogenic shock Shock, Cardiogenic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIOGENIC SHOCK

Contacts and locations

Locations

CHRU de Strasbourg
NOT_YET_RECRUITING

Strasbourg, 67000, France
CHU d'Amiens-Picardie
NOT_YET_RECRUITING

Amiens, 80000, France
CHU d'Orléans
NOT_YET_RECRUITING

Orléans, 45100, France
CHU de Toulouse
NOT_YET_RECRUITING

Toulouse, 31000, France
CMC Ambroise Paré - Hartmann
RECRUITING

Neuilly-sur-Seine, 92200, France
Centre Cardiologique du Nord
NOT_YET_RECRUITING

Saint-Denis, 93200, France
Clinique NCT + /Saint-Gatien
NOT_YET_RECRUITING

Saint-Cyr-sur-Loire, 37540, France
Hôpital Cochin
NOT_YET_RECRUITING

Paris, 75014, France
Hôpital Henri Mondor
NOT_YET_RECRUITING

Créteil, 94010, France
Hôpital Lariboisière
NOT_YET_RECRUITING

Paris, 75010, France
Hôpital Privé Jacques Cartier
NOT_YET_RECRUITING

Massy, 91300, France

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