Blood test guides cancer treatment: doctors try custom doses to boost survival, cut side effects

NCT ID NCT07425054

Summary

This study is testing a personalized approach to standard chemoradiation therapy for people with locally-advanced anal cancer. Doctors will use a blood test that detects tumor DNA to see how well the cancer is responding during treatment. Based on the test results, they will adjust the chemo-radiation dose up or down, aiming to improve survival while reducing side effects. Some participants whose cancer responds poorly may also receive an immunotherapy drug called retifanlimab.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Case Comprehensive Cancer Center, Cleveland Clinic Taussig Cancer Center

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University Hospitals Cleveland Medical Center, Seidman Cancer Center, Cleveland Clinic Taussig Cancer Center, Case Comprehensive Cancer Center

    Cleveland, Ohio, 44106, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.