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Massive study seeks to unlock secrets of faster surgical recovery

NCT ID NCT04606264

Knowledge-focused Sponsor: Jennifer Holder-Murray Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at over 3,000 adults having elective abdominal surgery to find the best combinations of standard care before, during, and after the operation. The goal was to see which approaches helped patients spend fewer days in the hospital, have less nausea and vomiting, and feel less pain. The results will help doctors improve recovery plans for future patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

3,395 people

The number who actually took part.

Started

May 2023

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria 1. Patient is seen in preoperative appointment prior to surgery 2. ≥ 18 years of age 3. Anticipated overnight hospital stay 4. Scheduled for elective abdominal surgery that utilizes ERP PowerPlans - placed into the patient's electronic chart at least one night before surgery 5. ERP Abdominal Complex Pathway PowerPlan (used for colorectal and gastrointestinal surgery) 6. ERP Bariatric Surgery Pathway PowerPlan 7. ERP Gynecology Oncology Pathway PowerPlan 8. ERP Whipple/Pancreas Pathway PowerPlan 9. ERP Open Liver Resection Pathway PowerPlan 10. Surgery is scheduled for one of the following UPMC sites: 11. UPMC Presbyterian Hospital 12. UPMC Passavant Hospital 13. UPMC Magee-Women's Hospital Exclusion Critera 1. Death is deemed to be imminent or inevitable 2. Patient is pregnant \< 18 years of age 3. Patients undergoing emergent/urgent surgery 4. Patients that are pregnant 5. Patients that have an eligible PowerPlan ordered less than one night before surgery

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Conditions

The condition(s) this trial relates to.

Postoperative Nausea and Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Perioperative optimization

Contacts and locations

Locations

  • UPMC Magee-Womens Hospital

    Pittsburgh, Pennsylvania, 15213, United States

  • UPMC Passavant

    Pittsburgh, Pennsylvania, 15237, United States

  • UPMC Presbyterian

    Pittsburgh, Pennsylvania, 15213, United States