Triple threat: new combo aims to shrink stomach tumors before surgery

NCT ID NCT07408609

First seen Feb 15, 2026 · Last updated May 24, 2026 · Updated 14 times

Summary

This study tests whether adding low-dose radiation and an immunotherapy drug (tislelizumab) to standard chemotherapy before surgery can improve outcomes for people with locally advanced stomach or gastroesophageal junction cancer. About 114 adults aged 20-80 with resectable tumors will be randomly assigned to receive either the combination or chemotherapy alone. The main goal is to see if the combination leads to a higher rate of complete tumor disappearance at the time of surgery.

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