Could fluctuating blood flow during surgery harm older hearts?
NCT ID NCT07786753
First seen Aug 26, 2026 · Last updated Aug 27, 2026 · Updated 1 time
Summary
This study looks at whether changes in blood flow during major cancer surgery are linked to signs of heart injury in patients aged 65 and older. Researchers will monitor blood flow throughout the operation and measure a heart damage marker before and 24 hours after surgery. The goal is to see if unstable perfusion during surgery might be associated with heart strain, which could help improve care for older surgical patients.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If a link is found, it could guide anesthesiologists to adjust care during surgery to reduce heart damage risk in older patients.
- What could go wrong
- This is an observational study, so it can only show an association, not cause and effect. Results may not apply to all patients or surgeries.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 70 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Geriatric patients aged 65 years or older undergoing major abdominal oncologic surgery who meet the predefined eligibility criteria and have preoperative and 24-hour postoperative troponin measurements. Intraoperative hemodynamic and perfusion parameters, including PI, PVI, and cerebral oxygen saturation measured by NIRS, will be monitored throughout surgery and recorded at 15-minute intervals.
- Ages
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65 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 65 years or older * Undergoing major abdominal oncologic surgery * Availability of preoperative and 24-hour postoperative troponin measurements * Complete intraoperative and postoperative patient monitoring records * Provision of written informed consent Exclusion Criteria: * Age younger than 65 years * Absence of preoperative or 24-hour postoperative troponin measurements * Incomplete intraoperative or postoperative patient monitoring records * Undergoing emergency surgery * Advanced heart failure * ASA Physical Status IV * Pulmonary artery pressure \>40 mmHg
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Ankara Dr. Abdurrahman Yurtaslan Oncolgy Training and Research Hospital
Yenimahalle, Ankara, 06200, Turkey (Türkiye)