Can a simple drug combo ease radiation damage in head and neck cancer survivors?

NCT ID NCT03723291

First seen Mar 10, 2026 · Last updated May 15, 2026 · Updated 6 times

Summary

This study looked at whether adding pentoxifylline and vitamin E to standard rehabilitation exercises helps reduce fibrosis (stiffness) caused by radiation therapy in head and neck cancer survivors. Fifty adults who had radiation at least a year ago and were cancer-free took part. The main goal was to see if a larger trial is possible, not to prove the treatment works.

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Contacts and locations

Locations

  • Aintree University Hospital NHS Foundation Trust

    Liverpool, United Kingdom

  • University College London Hospitals NHS Foundation Trust

    London, United Kingdom

Conditions

Explore the condition pages connected to this study.