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Could a tiny ear device replace opioids after cancer surgery?

NCT ID NCT05742711

Completed Symptom relief Sponsor: DyAnsys, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested a device that sends mild electrical pulses to the ear (called PENS) to see if it can reduce pain and the need for strong painkillers after surgery for endometrial or cervical cancer. 48 women who had open surgery took part. The goal was to find a safer, non-drug way to manage pain without the side effects of opioids.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Percutaneous Electrical Nerve Stimulator (PENS) device
What this could lead to
If it works, this could offer a non-drug way to manage pain after cancer surgery, reducing the need for opioids and their side effects.
What could go wrong
This is a small, completed trial with only 48 people. The device may not work better than a sham device, and results may not apply to all surgeries or cancers.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cervical carcinoma endometrial cancer endometrium neoplasm Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANCER OF CERVIX CANCER OF ENDOMETRIUM

Contacts and locations

Locations

  • Cancer Institute,(Wia)

    Chennai, Tamil Nadu, 600020, India

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