Heart clip aims to cut stroke risk in surgery patients
NCT ID NCT06203054
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a device called Penditure that clips shut the left atrial appendage, a small pouch in the heart, during other heart surgeries. The goal is to prevent blood clots from forming there and causing strokes. About 198 adults having heart surgery will be enrolled, and doctors will check if the clip works well and is safe.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Penditure™ Left Atrial Appendage Exclusion System (a clip device)
- What this could lead to
- If successful, this device could provide a safe and effective way to close the left atrial appendage during heart surgery, potentially lowering stroke risk.
- What could go wrong
- This is a post-market study, not a randomized trial, so results may not prove superiority over other methods. Device-related complications or incomplete closure are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ascension St. Vincent Heart Center
Carmel, Indiana, 46290, United States
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Barnes Jewish Hospital
St Louis, Missouri, 63110, United States
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Corewell Health
Grand Rapids, Michigan, 49503, United States
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Emory Saint Joseph's Hospital
Atlanta, Georgia, 30342, United States
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Houston Methodist Hospital
Houston, Texas, 77030, United States
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Lankenau Institute for Medical Research
Wynnewood, Pennsylvania, 19096, United States
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Mayo Clinic Saint Marys Campus
Rochester, Minnesota, 55905, United States
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Northwestern Memorial Hospital
Chicago, Illinois, 60611, United States
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ProMedica Toledo Hospital
Toledo, Ohio, 43606, United States
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Saint Joseph's Hospital Health Center
Syracuse, New York, 13203, United States
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Swedish Medical Center Cherry Hill
Seattle, Washington, 98112, United States
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UPMC Pinnacle Harrisburg Campus
Harrisburg, Pennsylvania, 17101, United States
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University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106, United States
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University of Michigan Health System
Ann Arbor, Michigan, 48109, United States
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University of Pittsburgh Medical Center UPMC Presbyterian
Pittsburgh, Pennsylvania, 15213, United States