Experimental drug targets rare blood cancer in patients out of options

NCT ID NCT03011372

Summary

This study tested an experimental drug called pemigatinib in 47 patients with rare blood cancers caused by a specific genetic change (FGFR1 rearrangement). These patients had either relapsed after previous treatments like stem cell transplants or weren't candidates for those treatments. Researchers measured how well the drug controlled the cancer and monitored side effects.

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Contacts and locations

Locations

  • Azienda Ospedaliero-Universitaria Careggi (Aouc)

    Florence, 50134, Italy

  • Centre Leon Berard

    Lyon, 69373, France

  • Chu de Nice - Hospital L Archet

    Nice, 06202, France

  • City of Hope National Medical Center

    Duarte, California, 91010, United States

  • Emory University - Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

  • Franciscan St. Francis Health

    Indianapolis, Indiana, 46237, United States

  • Guys and St Thomas Nhs Foundation Trust

    London, SE1 9RT, United Kingdom

  • Hospital Clinico Universitario de Valencia

    Valencia, 46010, Spain

  • Hospital Saint Louis

    Paris, 75475, France

  • Iii Med. Abteilung For Hematologie and Onkologie Hanuscfhkrankenhaus

    Vienna, 01140, Austria

  • Inselspital - Universitaetsspital Bern

    Bern, 03010, Switzerland

  • Johannes Wesling Klinikum Minden

    Minden, 32429, Germany

  • Kindai University Hospital

    Osaka, 589-8511, Japan

  • Mayo Clinic Arizona

    Phoenix, Arizona, 85054, United States

  • Md Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Medical University of Vienna

    Vienna, 01090, Austria

  • Ntt Medical Center Tokyo

    Tokyo, 141-8625, Japan

  • Ordensklinikum Krankenhaus Der Barmherzigen Schwestern Linz

    Linz, 04010, Austria

  • Ospedale Papa Giovanni Xxiii

    Bergamo, 24127, Italy

  • Oxford University Hospitals Nhs Foundation Trust

    Oxford, OX3 7LE, United Kingdom

  • Princess Margaret Cancer Center

    Toronto, Ontario, M5G 2M9, Canada

  • Stanford Cancer Institute

    Stanford, California, 94305, United States

  • Universitair Ziekenhuis (Uz) Leuven

    Leuven, 03000, Belgium

  • Universitaire Du Cancer de Toulouse Institut Claudius Regaud Iuct-Oncopole

    Toulouse, 31059, France

  • Universitatsklinikum Halle (Saale)

    Halle, 06120, Germany

  • Universitatsklinikum Jena

    Jena, 07740, Germany

  • Universitatsklinikum Leipzig

    Leipzig, 04103, Germany

  • Universitatsspital Zurich

    Zurich, 08091, Switzerland

  • University Hospital Mannheim

    Mannheim, 68167, Germany

  • University Medical Center Rwth Aachen

    Aachen, D-52074, Germany

  • University of Utah

    Salt Lake City, Utah, 84112, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

  • Weill Cornell Medical Centers

    New York, New York, 10021, United States

Conditions

Explore the condition pages connected to this study.