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Lung cancer treatment gets a Needle-Free upgrade: shot vs IV

NCT ID NCT06212752

Ongoing Disease control Sponsor: Merck Sharp & Dohme LLC Source: ClinicalTrials.gov ↗

First seen Nov 12, 2025 · Last updated May 15, 2026 · Updated 19 times

Summary

This study compares a new shot form of the immunotherapy drug pembrolizumab (given with chemo) to the standard IV version for adults in Japan with metastatic non-small cell lung cancer who haven't had treatment before. The main goal is to see if the shot provides similar drug levels in the body and is as safe as the IV infusion. About 39 participants are enrolled, and the study is active but no longer recruiting.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Fujita Health University ( Site 4406)

    Toyoake, Aichi-ken, 470-1192, Japan

  • Gunma Prefectural Cancer Center ( Site 4416)

    Otashi, Gunma, 373-8550, Japan

  • Juntendo University Hospital ( Site 4413)

    Bunkyo-ku, Tokyo, 1138431, Japan

  • Kanagawa Cardiovascular and Respiratory Center ( Site 4404)

    Yokohama, Kanagawa, 236-0051, Japan

  • Kansai Medical University Hospital ( Site 4408)

    Hirakata, Osaka, 573-1191, Japan

  • Kurashiki Central Hospital ( Site 4409)

    Kurashiki, Okayama-ken, 710-8602, Japan

  • Kurume University Hospital ( Site 4412)

    Kurume, Fukuoka, 830-0011, Japan

  • Miyagi Cancer Center ( Site 4401)

    Natori-shi, Miyagi, 981-1293, Japan

  • National Hospital Organization Hokkaido Cancer Center ( Site 4415)

    Sapporo, Hokkaido, 003-0804, Japan

  • National Hospital Organization Kyushu Cancer Center ( Site 4410)

    Fukuoka, 811-1395, Japan

  • National Hospital Organization Kyushu Medical Center ( Site 4411)

    Fukuoka, 810-8563, Japan

  • Nippon Medical School Hospital ( Site 4403)

    Tokyo, 113-8603, Japan

  • Osaka International Cancer Institute ( Site 4407)

    Osaka, 541-8567, Japan

  • Osaka Medical and Pharmaceutical University Hospital ( Site 4414)

    Takatsuki, Osaka, 569-8686, Japan

  • Saitama Prefectural Cancer Center ( Site 4402)

    Ina-machi, Saitama, 362-0806, Japan

  • Sendai Kousei Hospital ( Site 4400)

    Sendai, Miyagi, 9800873, Japan

  • Shizuoka Cancer Center ( Site 4405)

    Nagaizumi-cho,Sunto-gun, Shizuoka, 411-8777, Japan

  • Tochigi Cancer Center ( Site 4417)

    Utsunomiya, Tochigi, 320-0834, Japan

Conditions

Explore the condition pages connected to this study.

METASTATIC NON-SMALL CELL LUNG CANCER