New combo therapy aims to shrink hard-to-treat liver tumors

NCT ID NCT03457948

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 28 times

Summary

This study tests whether adding an immunotherapy drug (pembrolizumab) to either liver-directed treatments or a type of radiation therapy (PRRT) can shrink tumors in people with advanced neuroendocrine tumors that have spread to the liver. About 32 adults with well-differentiated tumors are taking part. The goal is to see if the combination works better than immunotherapy alone.

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Contacts and locations

Locations

  • University of California, San Francisco

    San Francisco, California, 94143, United States

Conditions

Explore the condition pages connected to this study.