New drug combo aims to stop head and neck cancer recurrence
NCT ID NCT05433116
First seen Dec 08, 2025 · Last updated Apr 28, 2026 · Updated 16 times
Summary
This study tests whether adding lenvatinib to pembrolizumab (immunotherapy) after standard chemoradiation can help prevent head and neck cancer from coming back. About 50 adults with advanced, PD-L1 positive cancer will receive either the combination or pembrolizumab alone as maintenance therapy. The main goal is to see if the combination improves how long patients live without their cancer returning.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEAD AND NECK SQUAMOUS CELL CARCINOMA are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Gemeinschaftspraxis Hämatologie-Onkologie
Dresden, Saxony, 01307, Germany
-
Hospital Chemnitz, Radiation Oncology
Chemnitz, Saxony, 09116, Germany
-
Saarland University Medical Center and Saarland University Faculty of Medicine, Clinic for Radiotherapy and Radiooncology
Homburg, Saarland, 66421, Germany
-
University Hospital Augsburg, Radiation Oncology
Augsburg, Bavaria, 86156, Germany
-
University Hospital Düsseldorf, Radiation Oncology
Düsseldorf, North Rhine-Westphalia, 40225, Germany
-
University Hospital Erlangen, Radiation Oncology
Erlangen, Bavaria, 91054, Germany
-
University Hospital Frankfurt/M, Center for Radiology
Frankfurt am Main, Hesse, 60590, Germany
-
University Hospital Giessen; Ear, nose and throat clinic
Giessen, Hesse, 35392, Germany
-
University Hospital Regensburg, Clinic and Polyclinic for Radiotherapy
Regensburg, Bavaria, 93053, Germany
-
University Hospital Ulm, Otolaryngology & Head and Neck Surgery
Ulm, Baden-Wurttemberg, 89070, Germany
Conditions
Explore the condition pages connected to this study.