New drug combo aims to keep head and neck cancer at bay

NCT ID NCT05433116

First seen Dec 08, 2025 · Last updated May 30, 2026 · Updated 22 times

Summary

This study looks at whether adding lenvatinib to pembrolizumab (a type of immunotherapy) after standard chemoradiation can help prevent head and neck cancer from coming back. About 50 adults with advanced, PD-L1 positive head and neck cancer will take part. The goal is to see if the combination improves how long people stay cancer-free compared to pembrolizumab alone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEAD AND NECK SQUAMOUS CELL CARCINOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Gemeinschaftspraxis Hämatologie-Onkologie

    Dresden, Saxony, 01307, Germany

  • Hospital Chemnitz, Radiation Oncology

    Chemnitz, Saxony, 09116, Germany

  • Saarland University Medical Center and Saarland University Faculty of Medicine, Clinic for Radiotherapy and Radiooncology

    Homburg, Saarland, 66421, Germany

  • University Hospital Augsburg, Radiation Oncology

    Augsburg, Bavaria, 86156, Germany

  • University Hospital Düsseldorf, Radiation Oncology

    Düsseldorf, North Rhine-Westphalia, 40225, Germany

  • University Hospital Erlangen, Radiation Oncology

    Erlangen, Bavaria, 91054, Germany

  • University Hospital Frankfurt/M, Center for Radiology

    Frankfurt am Main, Hesse, 60590, Germany

  • University Hospital Giessen; Ear, nose and throat clinic

    Giessen, Hesse, 35392, Germany

  • University Hospital Regensburg, Clinic and Polyclinic for Radiotherapy

    Regensburg, Bavaria, 93053, Germany

  • University Hospital Ulm, Otolaryngology & Head and Neck Surgery

    Ulm, Baden-Wurttemberg, 89070, Germany

Conditions

Explore the condition pages connected to this study.