Immunotherapy after standard care may delay lung cancer return

NCT ID NCT02316002

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether the immunotherapy drug pembrolizumab (Keytruda) can help people with oligometastatic non-small cell lung cancer (NSCLC) who have already completed curative treatment. Fifty-one participants received pembrolizumab every three weeks for up to 16 cycles. The main goal was to see how long they lived without the cancer growing or spreading. The trial is now complete.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
pembrolizumab (a drug that helps the immune system fight cancer)
What this could lead to
If successful, this could show that adding pembrolizumab after standard treatment helps keep lung cancer from coming back longer.
What could go wrong
This is a small Phase 2 study with only 51 participants, so results may not apply to everyone. Pembrolizumab can cause immune-related side effects like inflammation in the lungs, colon, or skin.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Abramson Cancer Center of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

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Other studies related to the condition(s) this trial covers.