New combo shows promise in bile duct cancer battle

NCT ID NCT04924062

First seen Apr 16, 2026 · Last updated May 15, 2026 · Updated 5 times

Summary

This study tested whether adding the immunotherapy drug pembrolizumab to standard chemotherapy helps people with advanced bile duct cancer live longer. It involved 158 Chinese adults whose cancer had spread or could not be removed by surgery. The main goal was to see if the combination improved overall survival compared to chemotherapy alone.

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Contacts and locations

Locations

  • 900 Hospital of the Joint ( Site 0137)

    Fuzhou, Fujian, 350025, China

  • Anhui Provincial Hospital ( Site 0140)

    Hefei, Anhui, 230001, China

  • Beijing Cancer Hospital ( Site 0138)

    Beijing, Beijing Municipality, 100036, China

  • First Affiliated Hospital of The Third Military Medical University ( Site 0130)

    Chongqing, Chongqing Municipality, 400038, China

  • Fudan University Shanghai Cancer Center ( Site 0160)

    Shanghai, Shanghai Municipality, 201315, China

  • Fujian Provincial Cancer Hospital ( Site 0154)

    Fuzhou, Fujian, 350014, China

  • Guangdong Provincial People s Hospital ( Site 0161)

    Guangzhou, Guangdong, 510080, China

  • Harbin Medical University Cancer Hospital ( Site 0133)

    Harbin, Heilongjiang, 610000, China

  • Hunan Cancer Hospital ( Site 0132)

    Changsha, Hunan, 410013, China

  • Hunan Provincial People Hospital ( Site 0142)

    Changsha, Hunan, 410005, China

  • Peking Union Medical College Hospital ( Site 0150)

    Beijing, Beijing Municipality, 100730, China

  • Renji Hospital Shanghai Jiaotong University School of Medicine ( Site 0158)

    Shanghai, Shanghai Municipality, 200127, China

  • Tangdu Hospital ( Site 0146)

    Xi’an, Shanxi, 710038, China

  • The 81st Hospital of PLA ( Site 0128)

    Nanjing, Jiangsu, 210031, China

  • The First Affiliated Hospital Zhejiang University ( Site 0136)

    Hangzhou, Zhejiang, 310003, China

  • The First Affiliated Hospital of Xi an Jiaotong University ( Site 0145)

    Xi’an, Shanxi, 710048, China

  • The First Hospital of Jilin University ( Site 0131)

    Changchun, Jilin, 130021, China

  • The Third Xiangya Hospital of Central South University ( Site 0157)

    Changsha, Hunan, 410013, China

  • Tianjin Medical University Cancer Institute & Hospital ( Site 0155)

    Tianjin, Tianjin Municipality, 300060, China

  • West China Hospital of Sichuan University ( Site 0147)

    Chengdu, Sichuan, 610041, China

  • Zhejiang Cancer Hospital ( Site 0134)

    Hangzhou, Zhejiang, 310022, China

  • Zhongshan Hospital Fudan University ( Site 0129)

    Shanghai, Shanghai Municipality, 200032, China

Conditions

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