New drug cocktails aim to tame tough prostate cancer

NCT ID NCT02861573

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 29 times

Summary

This study tests whether combining the immunotherapy drug pembrolizumab with other treatments can help men with a hard-to-treat form of prostate cancer that has spread and stopped responding to hormone therapy. About 1,200 participants will receive different drug combinations across ten groups. The goal is to see if these combinations can shrink tumors or slow the disease, while monitoring side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Call for Information (Investigational Site 0008)

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

  • Call for Information (Investigational Site 0016)

    RECRUITING

    Seattle, Washington, 98109, United States

  • Call for Information (Investigational Site 0019)

    RECRUITING

    Myrtle Beach, South Carolina, 29572, United States

  • Call for Information (Investigational Site 2041)

    RECRUITING

    Aurora, Colorado, 80045, United States

  • Call for Information (Investigational Site 2090)

    RECRUITING

    Germantown, Tennessee, 38138, United States

  • Call for Information (Investigational Site 2091)

    RECRUITING

    Cleveland, Ohio, 44195, United States

  • Call for Information (Investigational Site 2094)

    RECRUITING

    Portland, Oregon, 97239, United States

  • MSD Australia

    RECRUITING

    North Ryde, Australia

    Contact Phone: •••-•••-••••

  • MSD Comercializadora, S. de R.L. de C.V.

    RECRUITING

    Mexico City, Mexico

    Contact Phone: •••-•••-••••

  • MSD Denmark

    RECRUITING

    Glostrup Municipality, Denmark

    Contact Phone: •••-•••-••••

  • MSD France

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-••••

  • MSD Ireland (Human Health) Ltd.

    RECRUITING

    Dublin, Ireland

    Contact Phone: •••-•••-••••

  • MSD Italia S.r.l.

    RECRUITING

    Rome, Italy

    Contact Phone: •••-•••-••••

  • MSD Polska Sp. Z o.o.

    RECRUITING

    Warsaw, Poland

    Contact Phone: •••-•••-••••

  • MSD Sweden

    RECRUITING

    Stockholm, Sweden

    Contact Phone: •••-•••-••••

  • Merck Canada

    RECRUITING

    Kirkland, Quebec, H9H 4M7, Canada

    Contact Phone: •••-•••-••••

  • Merck Sharp & Dohme (New Zealand) Ltd.,

    RECRUITING

    Auckland, New Zealand

    Contact Phone: •••-•••-••••

  • Merck Sharp & Dohme BV

    RECRUITING

    Haarlem, Netherlands

    Contact Phone: •••-•••-••••

  • Merck Sharp & Dohme Ilaclari Ltd. Sti

    RECRUITING

    Istanbul, Turkey (Türkiye)

    Contact Phone: •••-•••-••••

  • Merck Sharp & Dohme Ltd.

    RECRUITING

    London, United Kingdom

    Contact Phone: •••-•••-••••

  • Merck Sharp and Dohme de Espana S.A.

    RECRUITING

    Madrid, Spain

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.