Immunotherapy boosts chemo to wipe out hidden leukemia cells
NCT ID NCT04214249
First seen Mar 20, 2026 · Last updated Jun 12, 2026 · Updated 10 times
Summary
This study tests whether adding the immunotherapy drug pembrolizumab to standard chemotherapy can better eliminate leftover cancer cells in adults newly diagnosed with acute myeloid leukemia (AML). About 49 participants receive either chemo alone or chemo plus pembrolizumab. The main goal is to see if the combination leads to a deeper remission by clearing minimal residual disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
Lebanon, New Hampshire, 03756, United States
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Mayo Clinic in Florida
Jacksonville, Florida, 32224-9980, United States
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Northwestern University
Chicago, Illinois, 60611, United States
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UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange, California, 92868, United States
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University of Alabama at Birmingham Cancer Center
Birmingham, Alabama, 35233, United States
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VCU Massey Comprehensive Cancer Center
Richmond, Virginia, 23298, United States
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Wake Forest Baptist Health - Wilkes Medical Center
Wilkesboro, North Carolina, 28659, United States
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Wake Forest University Health Sciences
Winston-Salem, North Carolina, 27157, United States
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Wake Forest University at Clemmons
Clemmons, North Carolina, 27012, United States
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Yale University
New Haven, Connecticut, 06520, United States
Conditions
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