Immunotherapy before surgery shows promise for early lung cancer

NCT ID NCT02818920

First seen Mar 23, 2026 · Last updated Apr 29, 2026 · Updated 7 times

Summary

This study tested giving the immunotherapy drug pembrolizumab before and after surgery for people with early-stage non-small cell lung cancer. The goal was to see if this approach is safe and does not delay surgery. 35 participants were enrolled. The study looked at how the drug affects immune cells in the tumor. While pembrolizumab is already approved for advanced lung cancer, its use in this earlier setting was experimental.

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Contacts and locations

Locations

  • Dartmouth-Hitchcock Medical Center

    Lebanon, New Hampshire, 03756, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

Conditions

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