Virus therapy shows promise in Hard-to-Treat colorectal cancer trial

NCT ID NCT07446322

First seen Mar 13, 2026 · Last updated May 16, 2026 · Updated 5 times

Summary

This study tests whether adding a virus-based drug called pelareorep to standard chemotherapy can help people with a specific type of advanced colorectal cancer that has stopped responding to initial treatment. About 60 adults whose cancer has spread and has certain genetic features (RAS mutation, MSS) will be randomly assigned to receive either the standard chemo combo or the standard chemo plus pelareorep. The main goal is to see if the combination shrinks tumors more effectively.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Central Alabama Research

    RECRUITING

    Homewood, Alabama, 35209, United States

  • Summit Health Cancer Center

    RECRUITING

    Florham Park, New Jersey, 07932, United States

Conditions

Explore the condition pages connected to this study.